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The pipeline readout amplifier is a switched charge sensitive amplifier (fig. 6). Before operation the internal reset signal is applied thus discharging the two capacitances (for clearness assume Vdcl= Vd). After the reset the pipeamp is sensitive to the pipeline capacitor charge; since the node at the inverting input stays on constant potential, the charge transfer between the two capacitors causes a related voltage on the output when coupling charge to the input.
The following strategy is recommended in case of radiation damage: